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Sodium bicarbonate is used for the treatment of metabolic acidosis which may occur in severe renal disease, uncontrolled diabetes, circulatory insufficiency due to shock or severe dehydration, extracorporeal circulation of blood, cardiac arrest and severe primary lactic acidosis

Finally, ceria-based nanocomposites simultaneously scavenge ROS, preserve mitochondrial integrity, and mitigate tubular damage, demonstrating synergistic intervention from stone formation [64]

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